Chromatin Regulatory Mechanisms in Pluripotency
October 5 - 8, 2008
This meeting will promote understanding of the role of chromatin regulatory mechanisms in pluripotency and will help resolve controversy surrounding the role of specific genes and processes. Current evidence suggests that stem cells have a specific chromatin state essential to their self-renewal and ability to give rise to multiple lineages. A number of genes have been implicated in establishing this pluripotent state, and some of these are also likely to be involved in reprogramming somatic nuclei to a pluripotent state. A clear understanding of these mechanisms could pave the way to the production of cell types and organs for regenerative medicine.
ORGANIZERS:
Gerald Crabtree, Stanford University
Julie Lessard, Université de Montréal
Janet Rossant, University of Toronto