Copyright (c) 2005 Howard Hughes Medical Institute. HHMI News http://www.hhmi.org/news/top_stories.html en-us Fri, 25 Jul 2008 17:18:44 -0400 Fri, 25 Jul 2008 17:18:44 -0400 30 http://www.hhmi.org/news/jessell20080725.html Researchers have revealed an important step in the process that guides the early development of neurons as they establish precise connections between the spinal cord and muscles. Fri, 25 Jul 2008 00:00:00 EST http://www.hhmi.org/news/jessell20080725.html http://www.hhmi.org/news/engle20080724.html An international team of researchers has identified a gene mutated in Duane syndrome, a common disorder that restricts the movement of the eyes. Thu, 24 Jul 2008 14:00:00 EST http://www.hhmi.org/news/engle20080724.html http://www.hhmi.org/news/sehgal20080717.html Thanks to a set of fruit flies that seem to get by with far less dozing than most, researchers has found a gene absolutely necessary for snoozing. Thu, 17 Jul 2008 00:00:00 EST http://www.hhmi.org/news/sehgal20080717.html http://www.hhmi.org/news/walsh20080711.html By focusing on large families in which both parents share a recent ancestor, scientists have honed in on rare mutations that had remained elusive in previous studies. Fri, 11 Jul 2008 00:00:00 EST http://www.hhmi.org/news/walsh20080711.html http://www.hhmi.org/news/20080710mootha.html HHMI-supported scientists have created MitoCarta, an online atlas of more than 1,000 proteins that healthy mitochondria use to keep cells running smoothly—a tool that should help researchers understand what happens when things go wrong. Its creators have used the resource to identify a genetic mutation responsible for complex I deficiency, a rare, lethal metabolic disorder in infants. Thu, 10 Jul 2008 12:00:00 EST http://www.hhmi.org/news/20080710mootha.html http://www.hhmi.org/news/20080709cowman.html After a malaria parasite invades a red blood cell, it sends a crew of proteins inside that gut the cell, transforming it from a vital oxygen delivery system into a nest for new parasites. HHMI international scholar Alan Cowman and his colleagues set out to understand the proteins that oversee this destruction and rebuilding. Wed, 09 Jul 2008 12:00:00 EST http://www.hhmi.org/news/20080709cowman.html http://www.hhmi.org/news/ahlquist20080709.html Scientists may be able to stave off influenza infection by targeting one of more than 100 proteins inside host cells on which the virus depends. These potential drug targets are the result of a study in which researchers tested the ability of a modified influenza virus to infect fruit fly cells. Wed, 09 Jul 2008 00:00:00 EST http://www.hhmi.org/news/ahlquist20080709.html http://www.hhmi.org/news/20080702pevzner.html Pavel Pevzner has created a class that turns undergraduates into experts on genome annotation. Without more bioinformatics specialists like his students, we’ll either we’ll drown in data or, worse, miss the key connections that undergird human health or disease, he says. The class has published their results in the journal Genome Research. Wed, 02 Jul 2008 12:00:00 EST http://www.hhmi.org/news/20080702pevzner.html http://www.hhmi.org/news/carlson20080620.html Marian Carlson will work from the Institute's headquarters to support the research of HHMI investigators across the nation. Fri, 20 Jun 2008 00:00:00 EST http://www.hhmi.org/news/carlson20080620.html http://www.hhmi.org/news/pourquie20080618.html Researchers have uncovered the mechanism that guides vertebral development in the early embryo and makes sure each species ends up with the right number of vertebrae. Wed, 18 Jun 2008 00:00:00 EST http://www.hhmi.org/news/pourquie20080618.html http://www.hhmi.org/news/orkin20080616.html HHMI researchers have developed a mouse model of osteosarcoma, the most common form of bone cancer. Mon, 16 Jun 2008 00:00:00 EST http://www.hhmi.org/news/orkin20080616.html http://www.hhmi.org/news/siliciano20080615.html A new model reveals that three classes of HIV drugs inhibit the virus more than 10,000 times better than others. Sun, 15 Jun 2008 00:00:00 EST http://www.hhmi.org/news/siliciano20080615.html http://www.hhmi.org/news/svoboda20080613.html Researchers have identified a chemical messenger that helps different sites on individual neurons coordinate with one another. Fri, 13 Jun 2008 00:00:00 EST http://www.hhmi.org/news/svoboda20080613.html http://www.hhmi.org/news/20080605earlycareerPS.html Scientists who bridge the gap between basic research and clinical medicine at 14 academic medical centers will get a boost at a vital time in their career, as part of a $7.1 million initiative from the Howard Hughes Medical Institute. Thu, 05 Jun 2008 09:00:00 EST http://www.hhmi.org/news/20080605earlycareerPS.html http://www.hhmi.org/news/20080605scholarsfellows.html Medical, dental and, for the first time, veterinary students will get a chance to conduct biomedical research full time for a year, as part of a $4 million initiative by the Howard Hughes Medical Institute. Thu, 05 Jun 2008 09:00:00 EST http://www.hhmi.org/news/20080605scholarsfellows.html